Complementary
Therapy

Glaucoma
Disease

Glaucoma Disease

A leading cause of blindness in the world, it is a progressive optic neuropathy often associated with increased intraocular pressure and characterized by progressive death of retinal ganglion cells (RGCs).¹ The European Glaucoma Society recognizes neuroprotection as an adjuvant treatment option in glaucoma² and there is evidence that coenzyme Q1O has a potential retinal neuroprotective action.^1,4-6 Topical CoQ1O has proved to be an effective therapy preventing RGC apoptosis and losing glaucoma-related models.^5* This is due to its anti-apoptotic, antioxidant and bioenergetic properties.^3,7

1. Nucci C, Tartaglione R, Cerulli A, Mancino R, Spanò A, Cavaliere F, et al. Int Rev Neurobiol 2007; 82: 397-406.
2. European Glaucoma Society. Terminology and Guidelines for Glaucoma. 4th Edition. 2014.
3. Qu J et al. Invest Ophthalmol Vis Sci 2009; 50: 1814-1818.
4. Guo L, Cordeiro MF. Prog Brain Res 2008; 173: 437-450.
5. Davis BM, Tian K, Pahlitzsch M, Brenton J, Ravindran N, Butt G, et al. Mitochondrion 2017; 36: 114-123.
6. Noh YH, Kim KY, Shim MS, Choi SH, Choi S, Ellisman MH, et al. Cell Death Dis 2013; 4: e820.
7. Fato R et al. Acta Ophthalmol 2010; 88(4): e150- 1.

COQUN^®

Complementary treatment to antihypertensive glaucoma therapy

COQUN^® eye drops contain CoQ10 and are specially formulated for patients with glaucoma. It is a complementary treatment to antihypertensive glaucoma therapy due to its capacity of counteracting the oxidative damages strictly related to this pathology.⁸ It has been demonstrated that COQUN^® can help improve retinal function.9 COQUN^® eye drops are preservative free, hypoallergenic, contact lens friendly and well tolerated.⁸

Protect the retinal ganglion cells.^3,4,10

Energise retinal function.⁹

Compatible with antihypertensive glaucoma therapy.⁸

COQUN^® should never replace medically supervised glaucoma medication.

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1. Nucci C, Tartaglione R, Cerulli A, Mancino R, Spanò A, Cavaliere F, et al. Int Rev Neurobiol 2007; 82: 397-406.
2. European Glaucoma Society. Terminology and Guidelines for Glaucoma. 4th Edition. 2014.
3. Qu J et al. Invest Ophthalmol Vis Sci 2009; 50: 1814-1818.
4. Guo L, Cordeiro MF. Prog Brain Res 2008; 173: 437-450.
5. Davis BM, Tian K, Pahlitzsch M, Brenton J, Ravindran N, Butt G, et al. Mitochondrion 2017; 36: 114-123
6. Noh YH, Kim KY, Shim MS, Choi SH, Choi S, Ellisman MH, et al. Cell Death Dis 2013; 4: e820.
7. Fato R et al. Acta Ophthalmol 2010; 88(4): e150-1.
8. COQUN® eye drops Instructions for Use, VISUfarma. [last revised 02/2020].
9. Parisi V et al. J Glaucoma 2014; 23(6): 391-404.
10. Lulli et al. Invest Ophthalmol Vis Sci 2012; 53(13): 8295-8302.

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Complementary Therapy

Glaucoma Disease

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Complementary
Therapy

Glaucoma
Disease

COQUN^®